Elizabeth Moule is a founding partner of Moule & Polyzoides, Architects and Urbanists, a Los Angeles-based firm specializing in urbanism in new and existing places, campus architecture and planning, civic architecture, and historic preservation and adaptive reuse. She has led the design of a series of the firm’s key architectural commissions, including the Robert Redford Building, the West Coast headquarters for the NRDC in Santa Monica, California; the Robert Redford Building is rated as one of the greenest buildings in the world with a LEED Platinum rating. Among numerous other projects are the design of the Arabian Canal Neighborhoods, for Dubai, the United Arab Emirates; the restoration and design of new housing for the Vista del Arroyo bungalows in Pasadena, California.; and the reconstruction effort following Hurricane Katrina for Biloxi, Mississippi. The firm's work is published widely and was shown in the Los Angeles Museum of Contemporary Art's exhibition "Urban Revisions."

Moule is CEO of Meridian Properties, a real estate development company dedicated to new urbanist infill development. She is a co-founder of the Congress for the New Urbanism (CNU) and an emeritus board member. She is a co-author of the Ahwanhee Principles, the state of California community-planning guidelines authored in 1991 for the Local Government Commission. Moule teaches as a visiting critic at universities in the United States and abroad. She lectures frequently on architecture and urbanism.

Moule received her bachelor’s degree in art from Smith College, attended the Institute for Architecture and Urban Studies, and obtained her master’s in architecture from Princeton University.